Peter Husen

Peter Husen
Postdoc

Department of Physics, Chemistry and Pharmacy
University of Southern Denmark
Campusvej 55, 5230 Odense M
Denmark


Room: Ø13-601b-1
Tel: +45-6550-2526
E-mail: phusen@sdu.dk

Curriculum Vitae

Research: I work on multiscale studies of the cytochrome bc1 protein complex, which is responsible for transport of electric charge across a cellular membrane as part of both the photosynthetic and respiratory pathways. The bc1 complex is, however, also believed to be a source of superoxide production, which is toxic to cellls suspected to be related to aging and age-related diseases. I apply a combination of molecular dynamics simulations with quantum chemical calculations to model electron and proton transfer processes within the complex and investigate possible mechanisms for superoxide production.

Development: I also take part in development of the scandinaVIan KIt for nanoscale modelinG (VIKING), which is a software toolkit tailored for addressing biomedical research problems using multiscale computational modeling techniques.

Publications

Mutations at the Qo site of the cytochrome bc1 complex strongly affect oxygen binding, Peter Husen, Ilia A. Solov'yov, Journal of Physical Chemistry B, 121, 3308-3317, (2017)
Charge transfer at the Qo-site of the cytochrome bc1 complex leads to superoxide production, Adrian Bøgh Salo, Peter Husen, Ilia A. Solov'yov, Journal of Physical Chemistry B, 121, 1771-1782, (2017)
Spontaneous Binding of Molecular Oxygen at the Qo-Site of the bc1 Complex Could Stimulate Superoxide Formation, Peter Husen, Ilia A. Solov'yov, Journal of the American Chemical Society, 138, 12150-12158, (2016)
Preparing giant unilamellar vesicles (GUVs) of complex lipid mixtures on demand: Mixing small unilamellar vesicles of compositionally heterogeneous mixtures, Tripta Bhatia, Peter Husen, Jonathan Brewer, Luis A. Bagatolli, Per L. Hansen, John H. Ipsen, Ole G. Mouritsen, Biochimica et Biophysica Acta (BBA) - Biomembranes, 1848, 3175 - 3180, (2015)
Fluid domain patterns in free-standing membranes captured on a solid support, Tripta Bhatia, Peter Husen, John H. Ipsen, Luis A. Bagatolli, Adam Cohen Simonsen, Biochimica et Biophysica Acta (BBA) - Biomembranes, 1838, 2503 - 2510, (2014)