Luise Jacobsen

Luise_image
Masters Student
Involved in projects

Department of Physics, Chemistry and Pharmacy
University of Southern Denmark

Email: lujac16@student.sdu.dk

Education:

2016-2019: Bachelor's in Physics, University of Southern Denmark (SDU)

2019-2021: Master’s in Physics, University of Southern Denmark (SDU)

Current project:

I work on an extensive and automated virtual drug screening procedure that through a series of increasingly refined steps, based on molecular docking, molecular dynamics simulation, and free energy perturbation, will create a straightforward pathway to obtain a potential drug candidate against a specified target.

Previous project:

Using molecular dynamics simulations, I investigated how specific mutations of the cytochrome bc1 complex in malarial parasites affect the inhibition mechanism of known malarial drugs in the complex.

Publications

Inhibition Mechanism of Antimalarial Drugs Targeting the Cytochrome bc1 Complex, Luise Jacobsen, Peter Husen, Ilia A. Solov'yov, Journal of Chemical Information and Modeling, 61, 1334−1345, (2021)