
Department of Physics, Chemistry and Pharmacy
University of Southern Denmark
Campusvej 55, 5230 Odense M
Denmark
Room: V12-603b-2
Tel: +45-6550-2532
E-mail: phusen@sdu.dk
Research: I work on multiscale studies of the cytochrome bc1 protein complex, which is responsible for transport of electric charge across a cellular membrane as part of both the photosynthetic and respiratory pathways. The bc1 complex is, however, also believed to be a source of superoxide production, which is toxic to cellls suspected to be related to aging and age-related diseases. I apply a combination of molecular dynamics simulations with quantum chemical calculations to model electron and proton transfer processes within the complex and investigate possible mechanisms for superoxide production.
Development: I also take part in development of the scandinaVIan KIt for nanoscale modelinG (VIKING), which is a software toolkit tailored for addressing biomedical research problems using multiscale computational modeling techniques.